Herpesvirus transport to the nervous system and back again. Cambridge University Press, Cambridge, UK ( 2007). Arvin A, Campadelli-Fiume G, Mocarski E et al. In: Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Comparative virion structures of human herpesviruses. 13 Whitley R, Kimberlin DW, Prober CG.Entry of herpes simplex virus type 1 (HSV-1) into the distal axons of trigeminal neurons favors the onset of nonproductive, silent infection. 12 Hafezi W, Lorentzen EU, Eing BR et al.Showed that a combination of axonal infection and type I IFN can promote the establishment of HSV latency in cultured sensory neurons.Interferon alpha induces establishment of alphaherpesvirus latency in sensory neurons in vitro. 11 De Regge N, Van Opdenbosch N, Nauwynck HJ, Efstathiou S, Favoreel HW.Differentiation of neurons restricts arbovirus replication and increases expression of the alpha isoform of IRF-7.
10 Schultz KLW, Vernon PS, Griffin DE.Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation. 9 Farmer JR, Altschaefl KM, O'Shea KS, Miller DJ.VSV replication in neurons is inhibited by type I IFN at multiple stages of infection. PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons. 7 Samuel MA, Whitby K, Keller BC et al.Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival. Toll-like receptor 3 has a protective role against West Nile virus infection. 5 Daffis S, Samuel MA, Suthar MS, Gale M Jr, Diamond MS.Demonstrated that the magnitude and quality of antiviral responses is dependent upon neuronal subtype.Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. 4 Cho H, Proll SC, Szretter KJ, Katze MG, Gale M Jr, Diamond MS.Rowe AM, Leger AJ, Jeon S, Dhaliwal DK, Knickelbein JE, Hendricks RL. Recent issues in herpes simplex encephalitis. Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. 1 Arvin A, Campadelli-Fiume G, Mocarski E et al.Papers of special note have been highlighted as:
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